ICAM-1 | B7.1 | B7.2 | CD40 | TNF-α | IFN-γ | Proliferation | |
---|---|---|---|---|---|---|---|
nM | |||||||
AGE-2 | |||||||
PGE2 | 7 ± 0.2 | 7 ± 0.2 | 8 ± 0.3 | 8 ± 0.2 | 7 ± 0.2 | 8 ± 0.3 | 7 ± 0.3 |
ONO-AE1-259-01 | 9 ± 0.2 | 10 ± 0.1 | 10 ± 0.1 | 8 ± 0.3 | 7 ± 0.2 | 8 ± 0.2 | 7 ± 0.2 |
ONO-AE1-329 | 9 ± 0.2 | 10 ± 0.2 | 10 ± 0.1 | 10 ± 0.2 | 10 ± 0.2 | 10 ± 0.2 | 10 ± 0.3 |
AGE-3 | |||||||
PGE2 | 8 ± 0.3 | 8 ± 0.1 | 10 ± 0.2 | 15 ± 0.3 | 8 ± 0.3 | 8 ± 0.1 | 7 ± 0.4 |
ONO-AE1-259-01 | 8 ± 0.2 | 10 ± 0.1 | 10 ± 0.2 | 8 ± 0.2 | 7 ± 0.2 | 8 ± 0.2 | 8 ± 0.2 |
ONO-AE1-329 | 9 ± 0.2 | 10 ± 0.1 | 10 ± 0.2 | 10 ± 0.1 | 10 ± 0.3 | 10 ± 0.1 | 10 ± 0.2 |