Table 1

Kinetic values for inactivation and partition ratios for the WT and T205A mutant P450s inactivated by BPA and BMP^a

Inactivator	P450	K_I	k_inact	k_inact/K_I	Partition Ratio^b
		μM	min ⁻¹	min ⁻¹ mM ⁻¹
BPA	WT	0.7	1.64	2343	1
	T205A	16	0.36	23	9
BMP	WT	17	0.56	33	10
	T205A	16	0.14	9	35

↵a The kinetic values were determined as described under Materials and Methods and in Fig. 2.
↵b The partition ratios were determined as described in Fig. 3.