TABLE 2
Potency of APD791 and metabolites obtained in human 5-HT
2A
inositol phosphate accumulation assays
Compound
IC
50
nM ±S.E.M. (n)
APD791
5.2 ± 1.6 (3)
APD791-M1
1.7 ± 0.42 (3)
APD791-M2
6.1 ± 0.27 (3)