TABLE 2

Chemical structure and binding affinity of ligands competing with [³H]PGE₂ for binding to recombinant EP₄ receptors

K_i values of all ligands represent binding affinity for human EP₄ receptors, with the exception of 16,16-dimethyl PGE₂ and PGE₁ alcohol for which data for binding to murine EP₄ receptors are presented.