Females | Males | ||||||
---|---|---|---|---|---|---|---|
n | Slope | pA2a (pKB) | n | Slope | pA2 (pKB) | ||
Ro15-4513 (1.0 g/kg ethanol training) | |||||||
3123 | 5 | −1.53 | 5.40 | 4865 | 3 | −1.39 | 7.46 |
2830 | 4 | −1.20 | 6.55 | 4889 | 4 | −0.43 | 6.54 |
2852 | 4 | −0.63 | 6.20 | 4867 | 4 | −>0.38 | NC |
2913 | 4 | −1.13 | 6.92 | 4995 | 1 | NC | (6.68) |
4892 | 2 | NC | (6.68) | ||||
4864 | 1 | NC | (6.46) | ||||
Mean | −1.12 | 6.27 | Mean | −0.48 | 7.00 (6.63) | ||
95% CI | −0.40, −1.85 | 5.00, 7.53 | 95% CI | 1.26, −2.22 | 5.73, 8.27 (6.39, 6.87) | ||
Ro15-4513 (2.0 g/kg ethanol training) | |||||||
3220 | 3 | −0.80 | 6.48 | 4891 | 3 | −1.36 | 6.35 |
5400 | 1 | NC | (5.52) | 4890 | 2 | NC | (5.88) |
2835 | 1 | NC | (7.21) | 5496 | 0 | ||
5999 | 2 | NC | (5.90) | ||||
Mean | −0.80 | 6.48 (6.13) | Mean | −1.36 | 6.35 (5.88) | ||
95% CI | NC | NC (4.48, 7.79) | 95% CI | NC | NC (5.59, 6.17) | ||
Flumazenil (1.0 g/kg ethanol training) | |||||||
3123 | 3 | −0.74 | 4.57 | 4865 | 3 | 0.00004 | NC |
2830 | 2 | NC | (5.00) | 4892 | 1 | NC | (5.33) |
2852 | 2 | NC | (4.79) | 4867 | 2 | NC | (4.77) |
2913 | 1 | NC | (4.76) | 4864 | 2 | NC | (4.49) |
Mean | −0.74 | 4.57 (4.86) | Mean | 0.00004 | NC (4.77) | ||
95% CI | NC | NC (4.41, 5.32) | 95% CI | NC | NC (4.05, 5.49) | ||
Flumazenil (2.0 g/kg ethanol training) | |||||||
3220 | 2 | NC | (4.77) | 4891 | 3 | −0.81 | 5.10 |
5999 | 2 | NC | (3.63) | 4890 | 1 | NC | (4.64) |
Mean | NC | (4.20) | Mean | −0.81 | 5.10 (4.64) | ||
95% CI | NC | (2.66, 5.74) | 95% CI | NC | NC |
↵a For all pA2 analyses slopes were constrained to −1; NC, not calculable.