TABLE 2

Radiological toxicity of rats treated with infusates 0 to 4


Toxicity Type

Radiological Change

Infusate 1, No. of Rats

Infusate 2, No. of Rats

Infusate 3, No. of Rats

Infusate 4, No. of Rats
Hydrocephalus Depicted in T2 immediately after infusion and remained stable, except for one rat (hydrocephalus resolved on the second follow-up MRI) 1 1 1 1
Minor tissue damage along catheter insertion path Depicted on T2 MRI and DWMRI 2 1 1 1
Bleeding in the striatum
Depicted on T2 and DWMRI in the first follow-up and was recovered by the second follow-up MRI

1

1
  • DWMRI, diffusion-weighted magnetic resonance imaging