Resting membrane potential measurements (RMP) in control and in ACh in the presence and absence of phenylephrine
WKY | SHR | SHR + Enalapril | |
|---|---|---|---|
| Without phenylephrine | |||
| RMP | –52 ± 0.4 mV (8) | –49 ± 0.9 mV (10) | –51 ± 0.9 mV (10) |
| RMP in ACh (1 μM) | –72 ± 1.0 mV (7) | –62 ± 1.6 mV (6)* | –69 ± 1.3 mV (6) |
| With phenylephrine (1 μM) | |||
| RMP | –39 ± 0.9 mV (8) | –40 ± 0.7 mV (8) | –41 ± 0.7 mV (7) |
| RMP in ACh (1 μM) | –69 ± 1.3 mV (6) | –60 ± 1.5 mV (6)* | –70 ± 1.7 mV (5) |
↵* P < 0.05, when compared with WKY or SHR-enalapril, one-way ANOVA; mean ± S.E.M. Numbers in parentheses represent number of rats