Descriptive statistics for ECG parameters in saline control (n = 50) and GAP-134-treated (n = 50; 50 mg/kg) groups All values are expressed as mean ± S.E.M.
Phase | Saline Control | GAP-134 | |
|---|---|---|---|
| HR (bpm) | Predose | 92 ± 4.2 | 93 ± 3.8 |
| Postdose | 105 ± 4.2 | 111 ± 4.4 | |
| PR (ms) | Predose | 96 ± 1.4 | 96 ± 1.6 |
| Postdose | 93 ± 1.4 | 92 ± 1.4 | |
| QRS (ms) | Predose | 47 ± 1.1 | 45 ± 1.1 |
| Postdose | 45 ± 1.0 | 44 ± 1.0 | |
| QT (ms) | Predose | 212 ± 3.3 | 208 ± 2.7 |
| Postdose | 197 ± 2.7 | 191 ± 3.3 | |
| QTc (ms) | Predose | 201 ± 1.4 | 198 ± 1.6 |
|
| Postdose | 194 ± 1.4 | 192 ± 1.7 |