Rates of responding (per second) after injection with various drugs and doses in mice trained to discriminate 1.5 mg/kg S(+)-MDMA from saline
Dose | MDMA | S(+)-MDMA | R(–)-MDMA |
|---|---|---|---|
| Saline | 0.91 ± 0.26a | ||
| 0.03 | 0.55 ± 0.13 | 0.54 ± 0.37 | 0.49 ± 0.15 |
| 0.1 | 0.43 ± 0.13 | 0.32 ± 0.19 | 0.48 ± 0.17 |
| 0.3 | 0.31 ± 0.16 | 0.33 ± 0.14 | 0.35 ± 0.17 |
| 1.0 | 0.21 ± 0.15 | 0.19 ± 0.09 | 0.32 ± 0.24 |
| 1.5 |
| 0.22 ± 0.06a |
|
↵ a Response rates obtained in training sessions initiated by a single injection of either saline or the S(+)-MDMA training dose; all other rates were obtained in test sessions using cumulative dosing