Hemodynamic and coronary flow data
DMPO Concentrations | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 mM | 0.5 mM | 1 mM | 5 mM | 10 mM | |||||||||||||||
| Basal | End Reflow | Basal | End Reflow | Basal | End Reflow | Basal | End Reflow | Basal | End Reflow | ||||||||||
| LV systolic pressure (mm Hg) | 171.5 ± 11.0 | 141.1 ± 8.4 | 142.5 ± 12.5 | 136.3 ± 2.5 | 162.1 ± 6.5 | 145.0 ± 4.3 | 159.2 ± 18.0 | 142.8 ± 1.8 | 156.3 ± 6.9 | 132.8 ± 5.0 | |||||||||
| LV EDP (mm Hg) | 9.4 ± 0.4 | 117.8 ± 6.1 | 8.7 ± 2.1 | 92.8 ± 8.3 | 8.9 ± 0.7 | 79.1 ± 4.8 | 9.3 ± 1.2 | 84.5 ± 7.3 | 8.8 ± 0.9 | 87.7 ± 3.2 | |||||||||
| LVDP (mm Hg) | 162.1 ± 11.1 | 23.3 ± 5.2 | 133.8 ± 14.4 | 43.5 ± 6.0 | 153.2 ± 6.4 | 65.9 ± 7.8 | 150.0 ± 18.8 | 58.3 ± 6.3 | 147.6 ± 7.5 | 45.2 ± 5.7 | |||||||||
| HR (beats/min) | 269.3 ± 6.4 | 255.3 ± 37.7 | 297.8 ± 5.5 | 314.0 ± 13.5 | 290.6 ± 6.9 | 316.0 ± 6.7 | 297.3 ± 12.2 | 294.0 ± 23.4 | 290.0 ± 9.4 | 280.0 ± 13.0 | |||||||||
| RPP (103 mm Hg/min) | 43.6 ± 2.6 | 50.5 ± 0.8 | 40.0 ± 4.9 | 13.7 ± 2.1 | 44.8 ± 2.8 | 20.6 ± 2.1 | 44.1 ± 4.6 | 17.2 ± 2.4 | 42.6 ± 1.8 | 12.9 ± 1.9 | |||||||||
| CF (ml/min) | 17.1 ± 0.9 | 9.3 ± 0.9 | 18.0 ± 2.4 | 11.8 ± 3.3 | 15.6 ± 0.7 | 11.0 ± 1.1 | 16.3 ± 0.8 | 11.4 ± 1.2 | 17.8 ± 0.7 | 12.9 ± 2.0 | |||||||||
Data are mean ± S.E.M.