TABLE 2

Maximal response and potency of 3-pyr-Cyt used in this study on inhibition of the response to 30 μM ACh


Drug

Subunit

Inhibition of 30 μM Ach-Evoked Response
n
IC50
3-pyr-Cyt
Mixed α4β2
–0.8 ± 0.1
60 ± 12