Control Group | Treated Group | |
---|---|---|
Body weight (g) | 28.0 ± 1.5 | 27.3 ± 1.1 |
Tissue weight (% of body weight) | ||
Heart | 0.400 ± 0.031 | 0.427 ± 0.011 |
Kidney | 1.313 ± 0.105 | 1.328 ± 0.025 |
Spleen | 0.331 ± 0.024 | 0.306 ± 0.011 |
Liver | 4.687 ± 0.316 | 4.636 ± 0.030 |
α-Gal A activity (U/mg protein) | ||
Heart | 57.3 ± 2.2 | 2841.7 ± 246.4* |
Kidney | 67.1 ± 3.7 | 257.0 ± 28.3* |
Spleen | 122.8 ± 2.8 | 309.7 ± 40.7† |
Liver | 132.1 ± 13.9 | 267.7 ± 22.8† |
Biochemicals | ||
AST (U/l) | 75.3 ± 9.7 | 79.8 ± 8.4 |
ALT (U/l) | 31.0 ± 4.6 | 28.3 ± 1.3 |
LDH (U/l) | 305.5 ± 33.9 | 391.5 ± 43.4 |
BUN (mg/dl) | 23.67 ± 1.20 | 26.25 ± 2.96 |
Creatinine (mg/dl) | 0.90 ± 0.51 | 1.38 ± 0.45 |
Hematology profile | ||
Leukocytes | ||
White blood cells (K/μl) | 7.43 ± 3.24 | 4.06 ± 0.75 |
Neutrophils (K/μl) | 3.62 ± 2.08 | 1.20 ± 0.30 |
Lymphocytes (K/μl) | 3.51 ± 1.28 | 2.69 ± 0.46 |
Monocytes (K/μl) | 0.24 ± 0.12 | 0.14 ± 0.01 |
Eosinophils (K/μl) | 0.05 ± 0.03 | 0.03 ± 0.01 |
Basophils (K/μl) | 0.01 ± 0.01 | 0.01 ± 0.01 |
Erythrocytes | ||
Red blood cells (M/μl) | 8.53 ± 0.90 | 8.20 ± 0.62 |
Hemoglobin (g/dl) | 13.98 ± 1.25 | 13.50 ± 1.04 |
Hematocrit (%) | 46.35 ± 4.51 | 44.35 ± 2.85 |
Mean corpuscular volume (fl) | 54.58 ± 1.03 | 54.25 ± 0.79 |
Mean corpuscular hemoglobin (pg) | 16.48 ± 0.40 | 16.48 ± 0.22 |
Mean corpuscular hemoglobin concentration (g/dl) | 30.20 ± 0.41 | 30.35 ± 0.52 |
Red cell distribution (%) | 18.00 ± 0.51 | 18.45 ± 0.25 |
Thrombocytes | ||
Platelet (K/μl) | 1038 ± 212 | 1124 ± 78 |
Median platelet volume (fl) | 7.28 ± 2.54 | 5.90 ± 1.14 |