TABLE 1
Mean (±S.E.M.) exposure of LGD-3303 from the oral high-dose experiment
Dose
AUC
0–6
μ
g · h/ml
10 mg/kg/day
0.15 ± 0.05
30 mg/kg/day
0.24 ± 0.10
100 mg/kg/day
0.56 ± 0.08
300 mg/kg/day
0.85 ± 0.07