TABLE 2

Agonist activity for stimulation of cAMP accumulation in CHO M₄ cells previously treated with pertussis toxin The data are from Fig. 3a. The data represent the mean estimates ± S.E.M. The values in parentheses beneath some of the estimates are the Log mean ± S.E.M.

Agonist	E_max ^a	EC₅₀	Hill Slope	RA_i
Agonist	E_max ^a	EC₅₀	Hill Slope			Null	Operational
	%	μM
Oxotremorine-M	106 ± 3.8	0.54 (–6.27 ± 0.06)	1.25 ± 0.21	11.80 (1.07 ± 0.04)	10.67 (1.03 ± 0.10)
Carbachol	78 ± 3.2	5.3 (–5.28 ± 0.07)	1.26 ± 0.24	1.0 (0.0)	1.0 (0.0)
S-Aceclidine	53 ± 5.7	11.8 (–4.93 ± 0.23)	1^b	0.39 (–0.41 ± 0.37)	0.45 (–0.35 ± 0.14)

↵ a Denotes the maximal stimulation of cAMP accumulation expressed as a percentage of basal cAMP accumulation, which is the amount of accumulation in the presence of forskolin (0.1 μM)
↵ b Hill slope constrained to 1