TABLE 1

Steady-state inactivation parameters



Fast Inactivation

Slow Inactivation

V1/2
k
n
V1/2
k
n
mV mV
Control –41.7 ± 1.8 9.2 ± 0.5 10 –47.5 ± 0.6 9.9 ± 0.5 9
YWI92 (30 μM) –51.7 ± 4.2a 11.7 ± 0.8a,b 5 –62.9 ± 1.7c 10.6 ± 0.4 5
LTG (30 μM)
–43.8 ± 2.9
8.2 ± 0.2
5
–58.3 ± 3.9c
9.9 ± 0.3
4
  • a P < 0.05 vs. control

  • b P < 0.01 vs. LTG

  • c P < 0.001 vs. control