Summary of the effect of increasing concentrations of EtOH on sIPSCs, eIPSCs, and eEPSPs Values represent percentage of control (calculated as the average of baseline and washout responses). Number of determinations is given in parentheses.
10 mM | 25 mM | 50 mM | |
|---|---|---|---|
| sIPSC | |||
| Frequency | Not determined | 115.6 ± 9.6 (4) | 136.9 ± 8.3* (6) |
| Amplitude | Not determined | 108.7 ± 8.7 (4) | 101.2 ± 5.5 (6) |
| eIPSC (proximal) | |||
| eIPSC1 amplitude | Not determined | Not determined | 95.9 ± 7 (8) |
| Paired pulse ratio | Not determined | Not determined | 98 ± 5.7 (8) |
| eIPSC (distal) | |||
| eIPSC1 amplitude | 83 ± 13 (4) | 141.4 ± 5.6** (4) | 126.5 ± 6.7** (8) |
| Paired pulse ratio | 103.4 ± 5 (4) | 77.6 ± 7* (4) | 87.6 ± 4.7* (8) |
| eEPSPs | |||
| eEPSP1 amplitude | 85.94 ± 5.6 (5) | 62.9 ± 9.4* (5) | 49.4 ± 11.5*** (4) |
| Paired pulse ratio | 101.3 ± 7.2 (5) | 125.9 ± 11.4 (5) | 117.8 ± 8.8 (4) |
| AP no. | 84.7 ± 10.8 (5) | 58.9 ± 14.7* (6) | 53.1 ± 13.3* (4) |