TABLE 1

Effects of desipramine (10 and 20 mg/kg i.p.) and fluoxetine (10 and 20 mg/kg i.p.) administered for 2 weeks after induction of colitis on ulcer score index of rats Values are expressed as mean ± S.E.M. (n = 8).


No.

Group

Ulcer Score Index
1 Normal 0.00 ± 0.00
2 Acetic acid control 4.63 ± 0.02*
3 10 mg/kg Desipramine 3.22 ± 0.04*#
4 20 mg/kg Desipramine 1.78 ± 0.03*#
5 10 mg/kg Fluoxetine 3.57 ± 0.03*#
6
20 mg/kg Fluoxetine
2.00 ± 0.06*#
  • * P < 0.001 in comparison with group 1 normal control

  • # P < 0.001 in comparison with group 2 AAIC control group