Parameter | AC-55541 | AC-264613 |
---|---|---|
Tmax (h) | 0.8 ± 0.2 | 0.2 ± 0.0 |
Cmax (ng/ml) | 1035 ± 40 | 1233 ± 395 |
t1/2 (h) | 6.1 ± 1.5 | 2.5 ± 2.0 |
AUCINF obs (h/ng/ml) | 7936 ± 997 | 1341 ± 448 |
MRTINF obs (h) | 6.9 ± 1.6 | 1.4 ± 0.4 |
Tmax, time of peak plasma concentration; Cmax, peak plasma concentration; t1/2, half-life of the compound in plasma; AUC, area under the curve; MRT, mean residence time