Effects of desipramine (10 and 20 mg/kg i.p.) and fluoxetine (10 and 20 mg/kg i.p.) administered for 2 weeks after induction of colitis on colonic-reduced glutathione concentration in rats Values are expressed as mean ± S.E.M., n = 8.
No. | Group | GSH mg/g Tissue |
|---|---|---|
| 1 | Normal | 1436 ± 57 |
| 2 | Acetic acid control | 639 ± 46* |
| 3 | 10 mg/kg Desipramine | 805 ± 87*# |
| 4 | 20 mg/kg Desipramine | 813 ± 74*# |
| 5 | 10 mg/kg Fluoxetine | 781 ± 19*# |
| 6 | 20 mg/kg Fluoxetine | 750 ± 20*# |