Symbol | Meaning | Formula | Parameters | References |
---|---|---|---|---|
Caf | Free cyt. Ca2+ (molar concentration) | Kd = 250 nM; Rmin = 0.24; Rmax = 0.86; β = 2.54 | (Grynkiewicz et al, 1985); from dye calibration | |
CaNCX | Ca2+ through INCX (moles) | 1/zF × ∫ dIm × dt | z = 1; F = Faraday constant | Bers, 2002a |
CaSRT | SR Ca2+ content (moles/Lcyt.) |
| CaNCX from caffeine pulse; Vcyt = Cm/6.44 |
Bers, 2002a
|
cyt., cytosol; Im, membrane current; Kd, dissociation constants; Rmin, Rmax, and β, indo-1 calibration parameters (Grynkiewicz et al, 1985); Vcyt, volume of cytosol