Exploratory behavior as measured by average rears (±S.E.M.) and vocalization (percentage of group) during the acetic acid-induced writhing assay in control, MD, and MW groups during the 1st and 20th episodes of withdrawal
Percentage Acetic Acid | Control | MD | MW (1st episode) | MW (20th episode) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rears | Vocalize | Rears | Vocalize | Rears | Vocalize | Rears | Vocalize | |||||
| % | % | % | % | |||||||||
| Vehicle | 18.2 ± 4.4 | 16.7 ± 15.2 | 2.2 ± 1.4 | 33.3 ± 19.3 | 5.3 ± 3.1 | 75.0 ± 17.9 | 3.8 ± 1.5 | 83.0 ± 17.9 | ||||
| 0.32 | 18.2 ± 3.1 | 0.0 ± 0.0 | Not done | Not done | 5.2 ± 2.2 | 66,7 ± 19.2 | 14.2 ± 4.0 | 83.0 ± 17.9 | ||||
| 1 | 21.2 ± 2.9 | 66.7 ± 19.3 | 2.8 ± 2.3 | 16.7 ± 15.2 | 1.8 ± 1.4 | 66.7 ± 19.2 | 4.7 ± 2.2 | 100.0 ± 0.0 | ||||
| 3.2 | 2.6 ± 1.5 | 83.3 ± 15.2 | 2.2 ± 1.4 | 50.0 ± 20.4 | 0.4 ± 0.4 | 80.0 ± 17.8 | 1.2 ± 1.0 | 100.0 ± 0.0 | ||||