TABLE 3
Pharmacodynamic parameter estimates for NTX in MM patients using a cellular bone homeostasis model
Parameter
Final Estimate
CV%
units
D
A
(day
-1
)
29.8
1.48
E
b
(nM)
5.55
6.73
EC
50
(pM)
1.88 × 10
-5
40.3
n
(dimensionless)
0.745
25.6