Profile | Control | Low Dose | High Dose | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(n = 13) | (n = 14) After Treatment | (n = 13) | (n = 12) | (n = 14) | (n = 11) | ||||||||||
Before Treatment | After Treatment | Before Treatment | After Treatment | Before Treatment | After Treatment | ||||||||||
Body weight (g) | 11.9 ± 0.591 | 14.0 ± 0.5 | 11.8 ± 0.4 | 13.6 ± 1.2 | 11.5 ± 0.8 | 13.5 ± 0.6 | |||||||||
Complete blood count and biochemical | |||||||||||||||
White blood cells (× 103/μl) | 3.9 ± 2.8 | 2.3 ± 0.7 | 2.7 ± 1.0 | ||||||||||||
Red blood cells (× 106/μl) | 7.8 ± 0.6 | 7.3 ± 0.6 | 7.3 ± 0.7 | ||||||||||||
Mean corpuscular volume (fl) | 46.4 ± 0.6 | 46.8 ± 0.8 | 47.7 ± 0.9 | ||||||||||||
Glutamic-oxaloacetic transaminase (U/l) | 581.1 ± 151.5 | 520.5 ± 169.9 | 630.7 ± 165.5 | ||||||||||||
Glutamic-pyruvic transaminase (U/l) | 87.2 ± 53.5 | 130.0 ± 119.9 | 137.3 ± 55.8 | ||||||||||||
BUN (mg/dl) | 25.5 ± 4.1 | 23.9 ± 3.2 | 24.8 ± 9.0 | ||||||||||||
Cr (mg/dl) |
|
| 0.43 ± 0.06 |
|
| 0.43 ± 0.05 |
|
| 0.48 ± 0.10 |