TABLE 2

Effect of 35 μM puromycin, 35 μM cycloheximide, and 10 μM MG132 on the proteasome function as measured by the MODC accumulation assay Data are shown as mean ± S.E.M. of three independent experiments.

MODC Accumulation
fluorescence units
Control 45 ± 15
Puromycin 37 ± 11
Cycloheximide 32 ± 11
MG132
156 ± 12***

  • ↵*** p < 0.001 vs. control (ANOVA, followed by Bonferroni's test)