Effect of in vitro incubation of atherosclerotic rabbit carotid artery rings with 20 μM puromycin for 3 or 7 days on the intimal- and medial area and the number of intact nuclei in the intima and media Data are shown as mean ± S.E.M.; n represents the number of rabbits.
3 Days | 7 Days | |||||
|---|---|---|---|---|---|---|
| Control (n = 5) | Puromycin (n = 5) | Control (n = 6) | Puromycin (n = 6) | |||
| Intimal area (mm2) | 0.30 ± 0.04 | 0.25 ± 0.04 | 0.38 ± 0.14 | 0.30 ± 0.07 | ||
| Medial area (mm2) | 0.76 ± 0.03 | 0.68 ± 0.03* | 0.68 ± 0.04 | 0.63 ± 0.04* | ||
| Intact nuclei/10–2 mm2 intima | 31 ± 2 | 15 ± 4* | 22 ± 4 | 4 ± 1* | ||
| Intact nuclei/10–2 mm2 media | 18 ± 1 | 10 ± 2* | 16 ± 1 | 2 ± 1* | ||
↵* p < 0.05 vs. control (Wilcoxon's signed rank test)