TABLE 1

Mean arterial pressure during basal, treatment, and recovery periods from each group Value was expressed as mean ± S.E., n = 5–7 in each group.

Basal
Treatment
Recovery
mm Hg
CAP 119 ± 6 118 ± 7 118 ± 6
CAPZ + CAP 125 ± 2 125 ± 2 124 ± 2
RP67580 + CAP 124 ± 3 124 ± 2 121 ± 2
L703, 606 + CAP 121 ± 6 122 ± 5 125 ± 5
CGRP8–37 + CAP 124 ± 3 122 ± 3 120 ± 4
SP 121 ± 5 120 ± 5 118 ± 4
CAPZ + SP 120 ± 4 120 ± 3 119 ± 4
CGRP 117 ± 5 118 ± 6 118 ± 5
CAPZ + CGRP
120 ± 4
123 ± 4
120 ± 4

  • RP67580, NK1 antagonist; L703,606, NK1 antagonist; CGRP8-37, CGRP receptor antagonist