Tissue weight and infarct size data Values are expressed as mean ± S.E.M., n = 8 to 11/group. Values in parentheses represent the number of animals with CHF in each group, expressed as a fraction.
Group | Body Weight | Heart Weight/BWa Ratio | Lung Weight/BW Ratio | % in CHF | Infarct Size | |
|---|---|---|---|---|---|---|
| g | mg/g | % | ||||
| 13-Wk post-MI animals | ||||||
| Sham | 295.6 ± 5.4 | 3.2 ± 0.1 | 3.7 ± 0.1 | —b (0/9) | — | |
| MI + Veh | 293.4 ± 4.8 | 3.6 ± 0.1* | 6.0 ± 0.4* | 72.7 (8/11) | 49.9 ± 2.5 | |
| MI + LT-RWJ | 291.6 ± 5.5 | 3.4 ± 0.1 | 4.5 ± 0.3*# | 20.0 (2/10) | 48.9 ± 1.5 | |
| MI + 1-wk RWJ | 294.7 ± 5.4 | 3.6 ± 0.1* | 5.7 ± 0.4* | 66.7 (6/9) | 48.4 ± 2.6 | |
| MI + Ram | 297.6 ± 11.6 | 3.4 ± 0.2 | 5.0 ± 0.3* | 30.0 (3/10) | 49.8 ± 2.9 | |
| 7-Day post-MI animals | ||||||
| Sham | 208.8 ± 7.0 | 3.2 ± 0.2 | 4.5 ± 0.1 | —(0/8) | — | |
| MI + Veh | 209.1 ± 5.1 | 4.0 ± 0.1* | 5.3 ± 0.2* | —(0/9) | 41.5 ± 1.9 | |
| MI + RWJ | 192.1 ± 7.3 | 3.6 ± 0.1* | 5.2 ± 0.2* | —(0/9) | 37.9 ± 2.1 | |