TABLE 1

Comparison of hindleg edema and blood pressure lowering of 1 mg/kg nifedipine between the SHR and SD rat Values are means ± S.E.M.


Animal

Hindleg Edema

Maximum MBP Lowering
% increase in integral T2 mm Hg
SHR 2606 ± 86 (n = 6) –77 ± 4 (n = 6)
SD rat
1439 ± 129* (n = 3)
–19 ± 3* (n = 3)
  • * p < 0.05, Student's t test; SHR vs. SD rat