Receptor | Lorcaserin Ki | Reference Compound (Ki) |
---|---|---|
nM | ||
Human 5-HT1A | 700 | 8-Hydroxy-2-dipropylaminotetralin (0.9) |
Human 5-HT3 | 4430 | MDL 72222 (7) |
Human 5HT4e | 18,900 | 5-HT (330) |
Human 5-HT5A | 3710 | 5-HT (69) |
Human 5-HT6 | 1980 | 5-HT (110) |
Human 5-HT7 | 636 | 5-HT (0.4) |
Human norepinephrine transporter | 1400 | Protriptyline (15) |
Human dopamine transporter | 33,000 | 1-[1-(2-Benzo[b]thienyl)cyclohexyl]piperidine (6.8) |
Human 5-HT transporter | 990 | Imipramine (1.3) |