TABLE 2

Statistical analysis of the combined effects of SR141716 and mCPP on response rate in mice trained to respond for Ensure under a progressive ratio schedule of reinforcement


SR/mCPP Ratio Based on Break Point/Response Rate

ED25 Predicted Additive (Zadd) ± S.E.M.

ED25 Observed (Zmix) ± S.E.M.

t

T

Significant?
1:1/2.8:1 4.542 ± 1.320 1.125 ± 0.444 2.455 2.293 Yes
2:1/6:1 3.914 ± 1.348 1.038 ± 0.116 2.126 2.264 No
3:1/9:1 3.749 ± 1.389 1.649 ± 0.817 1.304 2.341 No
1:2/1.5:1 5.071 ± 1.455 1.589 ± 0.328 2.330 2.278 Yes
1:3/1:1
4.933 ± 1.407
1.856 ± 1.355
1.575
2.410
No