X1 | X2 | Y5 | Y6 | L1 | L2 | L3 | Basal Response | Maximum Response | log (Maximum/Basal) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Positive agonists | ||||||||||||||||||
10-4 | 10-1 | 1 | 102 | 10-4 | 1 | 102 | 2.610-3 | 0.99 | 2.6 | |||||||||
10-4 | 10-1 | 10-4 | 102 | 10-4 | 1 | 102 | 2.610-3 | 0.66 | 2.4 | |||||||||
10-4 | 10-1 | 1 | 10-1 | 10-4 | 1 | 102 | 2.610-3 | 0.89 | 2.5 | |||||||||
10-4 | 10-1 | 10-1 | 10-1 | 10-4 | 1 | 102 | 2.610-3 | 0.66 | 2.4 | |||||||||
Inverse agonists | ||||||||||||||||||
10-4 | 10-1 | 10-5 | 10-1 | 10-4 | 1 | 102 | 2.610-3 | 4.4 × 10-4 | -0.8 | |||||||||
10-4 | 10-1 | 10-4 | 10-2 | 10-4 | 1 | 102 | 2.610-3 | 8.0 × 10-4 | -0.5 | |||||||||
10-4 | 10-1 |
10-5
|
10-2
| 10-4 | 1 | 102 | 2.610-3 | 2.6 × 10-4 | -1.0 |