TABLE 2

Effect of sHDL on cardiac function Data are expressed as area under the curve estimated accordingly to the trapezoid method from data recorded during the 30 min of reperfusion, mean ± S.E.M. Concentrations of sHDL are expressed as milligram of protein (peptide) per milliliter of buffer.






n

LVDP

CPP

CK
Saline 12 905 ± 35 1563 ± 70 5594 ± 213
sHDL (1 mg/ml) preischemia apoA-I 8 1369 ± 65*** 932 ± 51*** 2781 ± 167***
L37pA 4 1355 ± 58*** 902 ± 53*** 3054 ± 193***
D37pA 4 1385 ± 83*** 932 ± 56*** 2820 ± 146***
sHDL (2 mg/ml) at reperfusion apoA-I 6 1508 ± 65*** 816 ± 61*** 2868 ± 143***

L37pA
3
1203 ± 67**
1120 ± 83***
3679 ± 180***
  • ** P < 0.01 vs Saline

  • *** P < 0.001 vs Saline