Wild-Type (jvs+/+) | Heterozygous (jvs+/-) | |||||
---|---|---|---|---|---|---|
Vehicle | VPA | Vehicle | VPA | |||
Collection interval with the highest 14CO2 exhalation (minute) | 10-20 | 10-20 | 20-30 | 20-30 | ||
Peak exhalation (Percentage of injected dose/10 min) | 11.3 ± 0.8 | 10.7 ± 0.3 | 10.6 ± 0.4 | 8.6 ± 0.3*†‡ | ||
Cumulated 14CO2 exhalation (Percentage of injected dose/2 h) | 46.5 ± 3.9 | 41.7 ± 3.9 | 41.8 ± 3.9 | 33.5 ± 4.2† |