Standard liver function tests and serum electrolytes in cirrhotic rats with ascites receiving vehicle or the CB2 receptor agonist JWH-133 for 9 days
Vehicle (n = 7) | JWH-133 (n = 8) | |
|---|---|---|
| 1 mg · kg-1 · day-1 | ||
| Body wt (g) | 482 ± 3 | 459 ± 15 |
| Alanine aminotransferase (U/l) | 53.6 ± 8.7 | 89.0 ± 10.0 |
| Lactate dehydrogenase (U/l) | 620 ± 81 | 578 ± 98 |
| Total bilirubin (mg/dl) | 1.10 ± 0.26 | 1.10 ± 0.60 |
| Albumin (g/l) | 23.2 ± 1.3 | 26.3 ± 0.9 |
| Serum sodium (mEq/l) | 144 ± 1 | 143 ± 2 |
| Serum potassium (mEq/l) | 4.7 ± 0.4 | 4.0 ± 0.5 |
| Serum osmolality (mOsm/kg) | 293 ± 3 | 299 ± 3 |