No. | Compound | Nα-[methyl-3H]Histamine | [125I]Iodophenpropit | ||||
---|---|---|---|---|---|---|---|
hH3R(445) | hH3R(365) | hH3R(445) | hH3R(365) | ||||
1 | FUB322 | 7.7 ± 0.2 | 7.6 ± 0.1 | 7.2 ± 0.0 | 7.3 ± 0.1 | ||
2 | GT-2331 | 8.5 ± 0.2 | 8.9 ± 0.2 | 7.4 ± 0.1 | 8.2 ± 0.2 | ||
3 | Histamine | 8.6 ± 0.0 | 8.9 ± 0.1 | 6.2 ± 0.2 | 8.3 ± 0.1 | ||
4 | Imbutamine | 8.8 ± 0.1 | 9.3 ± 0.2 | 7.0 ± 0.10 | 8.9 ± 0.1 | ||
5 | Imetit | 9.4 ± 0.1 | 10 ± 0.2 | 7.7 ± 0.2 | 9.4 ± 0.2 | ||
6 | Imhexamine | 8.7 ± 0.1 | 8.5 ± 0.1 | 7.3 ± 0.0 | 7.7 ± 0.2 | ||
7 | Immepip | 9.4 ± 0.1 | 9.7 ± 0.1 | 8.1 ± 0.1 | 9.1 ± 0.2 | ||
8 | Imoproxifan | 7.1 ± 0.1 | 8.2 ± 0.2 | 6.8 ± 0.1 | 7.5 ± 0.1 | ||
9 | Impentamine | 8.5 ± 0.1 | 8.4 ± 0.1 | 7.6 ± 0.1 | 8.3 ± 0.1 | ||
10 | Nα-Methylhistamine | 9.0 ± 0.1 | 9.4 ± 0.1 | 7.3 ± 0.1 | 8.8 ± 0.2 | ||
11 | Proxyfan | 8.4 ± 0.2 | 8.9 ± 0.2 | 7.2 ± 0.1 | 8.2 ± 0.2 | ||
12 | (R)-α-Methylhistamine | 9.0 ± 0.1 | 9.1 ± 0.1 | 7.1 ± 0.2 | 9.0 ± 0.1 | ||
13 | (S)-α-Methylhistamine | 7.6 ± 0.2 | 8.7 ± 0.1 | 5.8 ± 0.2 | 8.0 ± 0.1 | ||
14 | VUF5681 | 8.9 ± 0.3 | 9.0 ± 0.2 | 7.5 ± 0.0 | 8.2 ± 0.1 | ||
15 | A-304121 | 6.6 ± 0.2 | 6.1 ± 0.1 | 5.8 ± 0.1 | 5.7 ± 0.2 | ||
16 | A-317920 | 7.4 ± 0.2 | 6.8 ± 0.2 | 6.8 ± 0.1 | 6.6 ± 0.2 | ||
17 | A-320436 | 8.1 ± 0.1 | 7.8 ± 0.1 | 8.4 ± 0.2 | 7.6 ± 0.2 | ||
18 | A-331440 | 8.0 ± 0.0 | 7.5 ± 0.2 | 7.9 ± 0.1 | 7.3 ± 0.2 | ||
19 | A-349821 | 9.2 ± 0.1 | 9.0 ± 0.1 | 9.8 ± 0.1 | 8.7 ± 0.1 | ||
20 | A-358239 | 9.1 ± 0.1 | 8.7 ± 0.2 | 9.7 ± 0.3 | 8.3 ± 0.3 | ||
21 | A-431404 | 9.4 ± 0.1 | 9.0 ± 0.1 | 9.5 ± 0.3 | 8.8 ± 0.2 | ||
22 | Ciproxifan | 7.4 ± 0.1 | 7.0 ± 0.1 | 7.2 ± 0.1 | 6.8 ± 0.1 | ||
23 | Clobenpropit | 9.3 ± 0.2 | 8.7 ± 0.1 | 9.1 ± 0.1 | 7.7 ± 0.2 | ||
24 | GT-2016 | 7.1 ± 0.1 | 6.3 ± 0.2 | 6.7 ± 0.1 | 6.6 ± 0.2 | ||
25 | Iodophenpropit | 9.1 ± 0.2 | 8.7 ± 0.2 | 8.4 ± 0.1 | 8.3 ± 0.1 | ||
26 | i-Propyl-impentamine | 8.3 ± 0.2 | 8.1 ± 0.1 | 7.5 ± 0.2 | 7.2 ± 0.1 | ||
27 | Thioperamide | 7.7 ± 0.2 | 7.8 ± 0.2 | 7.5 ± 0.01 | 6.8 ± 0.1 |