EC50 values for 5-HT-induced contraction of endothelium-denuded rat aorta
Antagonist | EC50 Value |
|---|---|
| -log mol / l | |
| Vehicle | 6.0 ± 0.1 |
| KTZ (10 μM) | 6.7 ± 0.3* |
| Vehicle | 5.9 ± 0.3 |
| l-NNA (100 μM) | 6.0 ± 0.2 |
| Vehicle | 5.8 ± 0.2 |
| ABT (0.5 mM) | 5.7 ± 0.2 |
| Vehicle | 5.7 ± 0.1 |
| Clotrimazole (10 μM) | 5.7 ± 0.1 |
| Vehicle | 5.8 ± 0.1 |
| 14,15-EEZE (10 μM) | 5.6 ± 0.1* |
↵* Statistically significant difference from the respective vehicle.