TABLE 2

The effect of MAP kinase inhibitors PD098059 and SB203580 on dextrosimendan (10 μM)-induced apoptosis in human eosinophils

Data are expressed as mean ± S.E.M., n = 5 to 7. The corresponding apoptotic index in the presence of IL-5 (10 pM) but in the absence of dextrosimendan was 0.15 ± 0.05.




Apoptotic Index
Mean ± S.E.M.
PD098059
    0 0.94 ± 0.01
    1 μM 0.95 ± 0.01
    10 μM 0.96 ± 0.01
SB203580
    0 0.91 ± 0.03
    1 μM 0.94 ± 0.01
    200 μM
0.95 ± 0.02