TABLE 1

Effect of acute cholecystitis, melatonin, and tempol treatment on oxidative stress markers

Data are expressed as mean ± S.E.M. of -fold increase respect to levels found in control tissue. n = 5 to 6 animals.




AC

DL

DL + MEL 2.5

DL + MEL 30

DL + MEL 4 Days

DL Tempol (1 mM)
MDA level 4.82 ± 0.43 4.32 ± 0.41 1.90 ± 0.37**,δδ 1.44 ± 0.26**,δδ 1.20 ± 0.26**,δδ 1.20 ± 0.21**,δδ
GSH level
0.31 ± 0.05
0.35 ± 0.05
0.76 ± 0.07*,δ
0.91 ± 0.06*,δ
0.89 ± 0.06*,δ
0.96 ± 0.04*,δ
  • * P < 0.05; ** P < 0.01 vs. AC.

  • δ P < 0.05; δδP < 0.01 vs. DL.