Effect of Aβ on endocannabinoid levels in C6 rat glioma cells
Measurement of endocannabinoid levels in C6 rat glioma cells 24 h after 1 μg/ml Aβ 1-42 challenge. The amount of endocannabinoids is expressed as picomoles per milligram of lipid extract. Results are the mean ± S.E.M. of four separate experiments in triplicate.
| Treatment | Lipid | ||
|---|---|---|---|
| AEA | 2-AG | PEA | |
| pmol/mg | |||
| ctrl | 3.2 ± 0.05 | 105 ± 11 | 32 ± 1.6 |
| Aβ 1 (μg/ml) | 0.8 ± 0.02* | 153 ± 16* | 33 ± 2 |
↵* p < 0.05 vs. unchallenged cells (ctrl).