Time for maximal cardiovascular effect produced by Bj-BPPs at different doses in SHRs and Wistar rats
Strain | Bj-BPP | Time for Maximal Change | ||||||
|---|---|---|---|---|---|---|---|---|
| 0.47 nmol/kg | 2.37 nmol/kg | 14.2 nmol/kg | 71 nmol/kg | |||||
| min | ||||||||
| SHR | BPP-7a | 257 ± 10 (range, 224-290) | 308 ± 14 (range, 272-348) | 248 ± 23 (range, 170-342) | 323 ± 13 (range, 278-354) | |||
| BPP-10c | 248 ± 28 (range, 160-334) | 294 ± 25 (range, 274-350) | 285 ± 29 (range, 192-358) | 345 ± 7 (range, 304-358) | ||||
| Wistar | BPP-7a | 250 ± 73 (range, 168-324) | N.D. | N.D. | 283 ± 13 (range, 242-310) | |||
|
| BPP-10c | 230 ± 33 (range, 178-356) | N.D. | N.D. | 246 ± 2 (range, 222-324) | |||
N.D., not determined.