In vitro potency of PF-670462 and literature standards
Data represent the mean ± S.E.M. for n = 3 to 5 determinations.
N.D., not determined; indicates that solubility and/or toxicity issues prevented reliable determination of an EC50 value.
↵ a Kinase-Glo assay (see Materials and Methods).
↵ b ArrayScan (Cellomics) (see Materials and Methods).