Predictor | SNP | P Value |
---|---|---|
VKORC1 | rs9923231 | <0.0001 |
CYP2C9 | rs1799853 (*2) | <0.0001 |
+ | ||
rs1057910 (*3) | ||
Age | 0.0029 | |
PROC | rs2069919 | 0.0416 |
Body weight | 0.0075 | |
EPHX1 | rs4653436 | 0.1016 |
Drug interaction | 0.0878 | |
GGCX | rs12714145 | 0.0260 |
ORM1 | rs1687390 | 0.0571 |
VKORC1, vitamin K epoxide reductase complex subunit 1 gene; CYP2C9, cytochrome P450 2C9 gene; PROC, protein C gene; EPHX1, microsomal epoxide hydrolase 1 gene; GGCX, γ-glutamyl carboxylase gene; ORM1, orosomucoid 1 gene or α-1-acid glycoprotein 1 gene.