TABLE 3

Effect of NU7026 on CLB cytotoxicity in I83 cell line using the MTT assay

Using the MTT assay, we evaluated the effect of NU7026 on CLB cytotoxicity in I83 cells. There is a significant difference (* p < 0.001) between the CLB IC50 alone vs. CLB IC50 in the presence of NU7026. Results are expressed as the mean value of four independent experiments ± S.D.




CLB IC50

NU7026 IC50

CLB + 10 μM NU7026 IC50

I Value
μM
I83 cells
11.69 ± 1.61
No death
3.35 ± 0.39* (3.5)a
0.29 ± 0.05
  • a Ratio between CLB IC50 alone/CLB IC50 in the presence of NU7026.