Antagonist effects of SB-705498 versus the acid-mediated activation of human and rat TRPV1 receptors Data are from experiments similar to those defined in the legend to Fig. 1 using a FLIPR Ca2+ plate-based assay and define the inhibition of acid-mediated responses of TRPV1 receptors expressed in HEK293 cells.
Cell Type | pIC50 | S.D. | n |
|---|---|---|---|
| HEK293-hTRPV1 | 7.1 | 0.1 | 36 |
| HEK293-rTRPV1 | 6.9 | 0.3 | 28 |
h, human; r, rat