TABLE 1

Antagonist effects of SB-705498 versus the capsaicin-mediated activation of human, rat, and guinea pig TRPV1 receptors Data are from experiments similar to those defined in the legend to Fig. 1, using a FLIPR Ca²⁺ plate-based assay (see Materials and Methods) and define the inhibition of (100 nM) capsaicin-mediated responses of TRPV1 receptors expressed in the cell lines or neurons indicated.