TABLE 5

Percentage of change in adrenergic receptor density in PFC and cortex following 2 weeks of continual DMI delivery compared with controls

The data from the DMI treated animals from Fig. 2 are expressed as a percentage of the control values.


Adrenergic Receptor Subtype

10 mg/kg/day DMI to Adult Rats

15 mg/kg/day DMI to PND 21 to 35 Rats
Cortex
PFC
Cortex
PFC
α-1 96 N.D. 79* N.D.
α-2 99 103 95 96
β
59*
54*
60*
52*
  • N.D. indicates areas that were not analyzed.

  • * Significantly different (p < 0.05) than control animals at same age by using the Student's t test.