Dose of VX-765 | VX-765 Parameter | VRT-043198 Parameter | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Cmax | Tmax | AUClast | Cmax | Tmax | AUClast | |||||
mg / kg | μg / ml | h | μg · h / ml | μg / ml | h | μg · h / ml | ||||
10 | 0.18 | 0.25 | 0.27 | 0.66 | 0.25 | 0.40 | ||||
21 | 0.23 | 3.0 | 0.91 | 2.14 | 0.17 | 1.90 | ||||
43 | 0.49 | 2.0 | 1.37 | 2.12 | 0.17 | 2.63 | ||||
84 | 0.78 | 1.0 | 2.06 | 3.26 | 0.17 | 8.66 |
AUC0-last, area under the curve calculated between time 0 and the last time point.