Normoxia | Normoxia + 10 pM AM | Normoxia + 100 pM AM | Hypoxia | |
---|---|---|---|---|
No intervention | 12.4 ± 1.0 | 11.3 ± 1.3 | 7.6 ± 1.0* | 20.4 ± 1.8* |
hCGRP(8-37) | 13.1 ± 0.8 | 11.9 ± 1.2 | 7.0 ± 1.2* | 19.4 ± 1.9* |
H89 | 12.1 ± 0.9 | 12.1 ± 0.9 | 7.9 ± 1.0* | 21.4 ± 2.2* |
KT-5720 | 12.7 ± 1.3 | 12.5 ± 1.0 | 8.2 ± 1.1* | 20.9 ± 1.7* |
hAM(22-52) | 11.9 ± 1.1 | 12.3 ± 1.1 | 11.1 ± 1.5 | 26.9 ± 2.0*† |
l-NOARG | 13.0 ± 0.8 | 13.3 ± 1.5 | 11.0 ± 1.5 | 28.9 ± 3.4*† |
KT-5823 | 11.8 ± 1.2 | 12.0 ± 1.3 | 11.4 ± 1.4 | 26.2 ± 2.3*† |
hAM(22-52) + l-NOARG | 12.8 ± 1.2 | 11.8 ± 1.2 | 11.8 ± 1.1 | 29.6 ± 2.9*† |
hAM(22-52) + KT-5823 | 12.6 ± 1.0 | 11.6 ± 0.8 | 12.1 ± 1.2 | 27.9 ± 2.4*† |
0.1% DMSO | 12.0 ± 1.0 | 11.8 ± 1.0 | 7.4 ± 1.0* | 20.0 ± 1.9* |