Affinity of RGH-237, BP-897, and SB-277011-A to rat dopamine D3, D2, α1-adrenergic, opiate, and 5-HT1A receptors
RGH-237 | BP-897 | SB-277011-A | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Ki | Selectivitya | Ki | Selectivitya | Ki | Selectivitya | ||||
| nM | nM | nM | |||||||
| D3 | 1.6 | 1 | 0.2 | 1 | 4.1 | 1 | |||
| D2 | >2900 | >1800 | 33 | 165 | >2900 | >700 | |||
| α1 | 1816 | 1135 | 10 | 50 | 3873 | 945 | |||
| Opiate | 129 | 81 | |||||||
| 5-HT1A | 245 | 153 |
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↵ a Ki for the receptor divided by Ki for D3 receptor