Venous blood gases
Values are means ± S.E.
Treatment | Min | pH | pCO2 | pO2* | BE** | HCO3-** | TCO2** | sO2* | Lactate* | |
|---|---|---|---|---|---|---|---|---|---|---|
| mm Hg | mM | % | mM | |||||||
| Pooled (n = 12) | 0 | 7.46 ± 0.01 | 44.5 ± 1.0 | 44.2 ± 1.7 | 7.8 ± 0.8 | 32.1 ± 0.6 | 33.3 ± 0.6 | 81.5 ± 1.6 | 0.97 ± 0.13 | |
| Saline (n = 9) | 25 | 7.25 ± 0.03 | 51.5 ± 2.6 | 21.3 ± 2.0 | -4.3 ± 1.8 | 22.9 ± 1.4 | 24.4 ± 1.6 | 28.7 ± 4.9 | 9.02 ± 0.86 | |
| 45 | 7.10 ± 0.0*** | 54.4 ± 5.2 | 31.2 ± 3.0*** | -13.0 ± 2.0† | 16.6 ± 1.4† | 18.3 ± 1.4† | 40.3 ± 7.8 | 13.47 ± 0.46† | ||
| 8-OH-DPAT (n = 7) | 25 | 7.29 ± 0.02 | 51.0 ± 2.4 | 23.0 ± 0.9 | -2.4 ± 1.0 | 24.2 ± 0.9 | 26.0 ± 1.0 | 33.0 ± 2.2 | 8.33 ± 0.47 | |
| 45 | 7.28 ± 0.03 | 54.7 ± 2.1 | 32.1 ± 2.0 | -5.6 ± 1.6†† | 22.2 ± 1.3†† | 23.7 ± 1.2†† | 48.1 ± 4.4 | 10.41 ± 0.72†† | ||
| Epinephrine (n = 8) | 25 | 7.31 ± 0.03 | 48.8 ± 2.1 | 27.0 ± 1.2 | -2.0 ± 1.3 | 24.3 ± 0.9 | 25.8 ± 0.9 | 43.9 ± 4.0 | 8.29 ± 0.77 | |
|
| 45 | 7.1 ± 0.07† | 60.2 ± 5.6 | 24.6 ± 2.7 | -11.3 ± 2.6†,††† | 18.5 ± 1.4†,††† | 20.5 ± 1.4†,††† | 28.1 ± 4.7 | 10.62 ± 1.21***,†† | |
BE, base excess; TCO2, total carbon dioxide.
↵* P < 0.05, overall interaction between time and treatment.
↵** P < 0.01, overall interaction between time and treatment.
↵*** P < 0.05, 25-min versus 45-min within-group.
↵† P < 0.01, 25-min versus 45-min within-group.
↵†† P < 0.01, versus saline.
↵††† P < 0.01 versus 8-OH-DPAT.